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饮食中食用活微生物与慢性病成年人死亡率之间的关系

Jianxin Han¹, Huan Zhang², Xinchun Li²

¹Department of Nephrology, The People's Hospital of Renshou County, The Second People's Hospital of Meishan City, Meishan, China.

Journal of nephrology

|February 12, 2025

概括

在食物中食用活微生物与慢性病 (CKD) 患者的死亡率降低有关. 摄入更多含有活微生物的食物 (MedHi) 显著降低了因所有原因和心血管疾病 (CVD) 死亡的风险.

科学领域:

微生物学和科微生物学和科
慢性疾病中的饮食干预
肠道微生物组研究研究

背景情况:

肠道失调与慢性病 (CKD) 有关.
饮食中活微生物摄入量对CKD预后的影响仍然不清楚.
这项研究调查了饮食中的活微生物与患有CKD的成年人死亡率之间的联系.

研究的目的:

检查饮食中的活微生物摄入量与患有CKD的成年人死亡率之间的关系.
为了确定食用活微生物是否会影响CKD患者的全因和心血管疾病 (CVD) 死亡率.

主要方法:

利用了来自国家健康和营养检查调查 (1999-2018) 的数据,其中包括8725名成年CKD参与者.
定义MedHi为饮食中的活微生物含量超过10^4 CFU/g.
使用加权多变量考克斯回归分析来评估MedHi摄入量与死亡率之间的关联.

主要成果:

与幸存者相比,没有生存的个体的饮食中活微生物摄入量较低.
增加MedHi食品的摄入量显示与减少全因和心血管疾病死亡率有线关联.
与那些摄入量最低的参与者相比,摄入量最高的MedHi食物的参与者具有20%较低的全因死亡风险和26%较低的心血管疾病死亡风险.

结论:

饮食中高摄入活微生物与慢性病患者的全因和心血管疾病死亡率相反相关.
饮食中的活微生物可能在CKD的预后中起着保护作用.
进一步研究CKD管理的饮食干预措施是有必要的.

关键词:

慢性脏疾病慢性脏疾病饮食中的活微生物肠道失调症是一种肠道失调症.死亡率死亡率死亡率

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