在 Amulet 和 Watchman FLX 之间进行选择的定量考虑以及与设备相关的并发症的管理
Alexander Kushnir1, Chirag R Barbhaiya2, Lior Jankelson2
1Leon H. Charney Division of Cardiology, Cardiac Electrophysiology, NYU Langone Health, New York University Grossman School of Medicine, 424 East 34th Street, KP 4th Floor, New York, NY, 10016, USA. Alexander.kushnir@nyulangone.org.
概括
观察者FLX推给左心房附属体解剖学有利的患者,以减少心周溢出,尽管它可能会增加周周器件泄漏. 联合手术可以减少并发症.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 包括Amulet和Watchman FLX在内的左心房尾阻塞 (LAA-O) 设备已获得FDA批准,用于降低心房患者中风风险.
- 关于临床结果和成像的真实数据对于设备选择和并发症管理至关重要.
研究的目的:
- 为了比较Amulet和Watchman FLX的临床结果和成像研究结果,左心房尾闭塞装置.
- 评估患者解剖学和联合手术对设备有效性和安全性的影响.
主要方法:
- 临床,食管横断心声学 (TEE) 和计算机断层扫描 (CT) 数据的回顾性分析.
- 在4年的时间里,包括了364个Watchman FLX和292个 Amulet程序.
- 评估手术成功,植入成功,心周溢出,与设备相关的血栓和周围设备泄漏 (PDL).
主要成果:
- FLX (96.7%) 和 Amulet (97.3%) 的程序成功率都很高.
- FLX显示晚期心周溢出率较低 (0.3%对Amulet为3.1%),但临床相关PDL的比率较高 (16%对Amulet为10%).
- 结合AF切除和LAA-O手术表明,PDL和晚期心周输液减少.
结论:
- 对于具有有利的LAA解剖的患者来说,Watchman FLX可能是首选的,以最大限度地减少心周溢出,接受更高的PDL风险.
- 护身符可能是一个合适的替代品,特别是当PDL是主要关注的问题时.
- 结合AF切除和LAA-O程序提供了改善的PDL和输液的结果.
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