在NHANES 2005-2020中对关节炎和过度活跃膀之间的关联有了新的见解
Yifan Sun1, Jiayi Sheng1, Ke Wang2
1Department of Urology, Jiangnan University Medical Center, Wuxi, China.
Scientific reports
|February 12, 2025
概括
关节炎与过度活跃的膀 (OAB) 有关,成年人患有关节炎的可能性增加了37%. 骨关节炎显示出显著的关联,但类风湿性和牛皮性关节炎没有.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 类风湿病学 类风湿病学
- 流行病学 流行病学
背景情况:
- 关节炎和过活性膀 (OAB) 是普遍存在的疾病,其病因关系不清楚.
- 了解潜在的联系对于全面的患者护理和管理策略至关重要.
研究的目的:
- 在大量成年人群中调查关节炎和过活性膀 (OAB) 之间的关联.
- 探索特定类型的关节炎是否与OAB患病率有不同的相关性.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 数据库 (2005-2020) 的数据.
- 通过过度活性膀症状评分 (OABSS) 诊断出OAB,并通过健康调查问卷诊断出关节炎.
- 使用加权后勤回归和子组分析与24436名参与者的相互作用测试.
主要成果:
- 在对共变量进行调整后,在关节炎和OAB之间发现了显著的积极关联 (OR = 1.37,95% CI: 1.22,1.54).
- 骨关节炎 (OA) 与OAB有显著的积极关联 (OR = 1.40,95% CI: 1.22,1.62).
- 对于类风湿性关节炎 (RA) 或牛皮性关节炎与OAB,没有发现显著的关联.
结论:
- 关节炎与过度活跃膀 (OAB) 的患病率增加有显著的关联.
- 骨关节炎似乎是这种关联的关键驱动因素,而其他形式的关节炎则需要进一步调查.
- 这些发现凸显了进一步研究的必要性,以阐明潜在的机制和临床影响.
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