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Updated: Jun 16, 2025

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
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在急性电离辐射中介的DNA损伤时,STING与PAR直接相互作用,促进细胞亡

Yirong Sun1,2, Saba R Aliyari3, Kislay Parvatiyar3,4

  • 1CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. sun_yirong@gibh.ac.cn.

Cell death and differentiation
|February 12, 2025
PubMed
概括

干扰素基因 (STING) 和多 (ADP-ribose) (PAR) 的刺激器对辐射诱导的亡至关重要. STING与PAR结合,促进细胞死亡,抑制这种途径可以防止辐射损伤和急性辐射综合征.

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