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Updated: May 28, 2025

Intravital Imaging of Axonal Interactions with Microglia and Macrophages in a Mouse Dorsal Column Crush Injury
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在重编程的微质中,H4K12乳激活-Spp1改善了脊髓损伤后的功能恢复

Xiaokun Wang1, Geliang Zhou2, Junjun Xiong1

  • 1Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

CNS neuroscience & therapeutics
|February 12, 2025
PubMed
概括

分泌的蛋白1 (SPP1) 促进神经元成熟和脊髓损伤 (SCI) 后的恢复. 这项研究揭示了SPP1的存在.

关键词:
SPP1 SPP1 这是一个很好的选择.基因素乳酸化 基因素乳酸化代谢重编程是指代谢重编程.微质细胞中的微质细胞脊髓损伤导致的脊髓损伤

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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