在接受息治疗的晚期癌症患者中妄的预测模型:开发和验证
Duan Guo1,2, Chuan Zhang1, Chaohui Leng3
1Department of Palliative Medicine, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan Province, China.
BMC palliative care
|February 12, 2025
概括
一个新的诺莫格拉姆模型有效地预测了接受息治疗的晚期癌症患者的妄想. 这种工具有助于早期干预,减少了与狂妄相关的痛苦.
科学领域:
- 抚慰性护理医学 抚慰性护理医学
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- 痴呆症是息治疗机构中常见的,令人痛苦的疾病.
- 现有的妄想预测模型对于息护理人群而言是缺乏的.
- 这项研究解决了在接受息治疗的晚期癌症患者中需要预测工具的需求.
研究的目的:
- 开发和验证一个用于预测妄想发生的诺莫格拉姆模型.
- 确定在临终护理中晚期癌症患者妄的独立风险因素.
- 为早期发现和预防妄想提供可靠的工具.
主要方法:
- 未来的,多中心的,观察性研究设计.
- 后勤回归分析以确定风险因素.
- 模型验证使用接收器操作特征曲线下的面积,校准图和决策曲线分析.
主要成果:
- 开发了一个纳米图模型,包括8个变量:年龄,查尔森并发症指数,认知功能,巴特尔指数,胆红素,,阿片类吗啡等效剂量和抗胆固醇药物的使用.
- 该模型表现出良好的性能,接收器操作特征曲线下的面积为0.846 (训练),0.829 (时间验证) 和0.803 (外部验证).
- 该模型显示出良好的区分,校准和临床可行性.
结论:
- 开发的诺米图谱是预测晚期癌症患者在息治疗中的妄想发作的可靠工具.
- 早期预测有助于采取有针对性的预防措施,以减少妄想的负担.
- 这种模式可以改善患者的治疗结果和息治疗环境中的护理质量.
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