通过营养肠道微生物组调节来应对全球健康挑战的弹性
Erika Isolauri1,2, Kirsi Laitinen3
1Department of Clinical Medicine, Faculty of Medicine, University of Turku, 20520 Turku, Finland.
Nutrients
|February 13, 2025
概括
非传染性疾病 (NCD) 和肥胖风险的早期开始. 在怀孕和婴儿期调节母亲的微生物组和营养提供了一个关键策略,以防止NCDs在未来几代人.
科学领域:
- 微生物组研究的研究.
- 发育生物学是发展生物学.
- 公共卫生 公共卫生
背景情况:
- 非传染性疾病 (NCD) 和肥胖症正在加剧全球卫生挑战.
- 异常的肠道微生物组成越来越多地与非传染性疾病和肥胖有关.
- 生命早期阶段代表了发展可塑性和长期健康规划的关键窗口.
研究的目的:
- 调查宿主微生物交叉在NCD发展中的作用.
- 确定针对肠道微生物群的干预措施的最佳时间.
- 探索母体微生物组和营养调节在NCD预防方面的潜力.
主要方法:
- 专注于怀孕期间和婴儿早期的宿主微生物相互作用.
- 分析肠道微生物群的组成和功能.
- 对宿主免疫和代谢成熟的营养影响的评估.
主要成果:
- 生命的早期,特别是怀孕和婴儿期,是免疫,代谢和微生物发展的关键时期.
- 母亲的微生物组和营养显著影响后代的长期健康轨迹.
- 在这个窗口期间的干预有望降低NCD风险.
结论:
- 通过微生物组和营养策略促进孕产妇健康可以改善后代的健康状况.
- 针对最早的环境暴露 (微生物组和营养) 是NCD预防的关键.
- 在生命早期了解宿主微生物交叉交流对于公共卫生倡议至关重要.
相关概念视频
Physiology of Enteric Nervous System and Gut Health
221
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
221
What is Monogastric Digestion?
70.4K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
70.4K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
304
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
304
Anatomy of the Intestines
71.2K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.2K
The Roles of Bacteria and Fungi in Plant Nutrition
34.9K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
34.9K


