微量元素对内分泌功能和甲状腺疾病的发病效应 - - 文学综述
Łukasz Bryliński1, Katarzyna Kostelecka2, Filip Woliński1
1Department of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.
Nutrients
|February 13, 2025
概括
微量元素对于甲状腺健康至关重要. 铁和等必需矿物质的不平衡,或接触等重金属,可以显著增加各种甲状腺疾病的风险.
科学领域:
- 内分泌学 在内分泌学.
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
背景情况:
- 甲状腺需要特定的微量元素来实现最佳功能.
- 外部因素,包括微量元素,显著影响甲状腺健康.
- 微量元素的不平衡与许多甲状腺病理有关.
研究的目的:
- 审查微量元素在甲状腺功能中的多方面的作用.
- 阐明基本和有毒微量元素对甲状腺健康的影响.
- 要突出微量元素失调与甲状腺疾病发展之间的关联.
主要方法:
- 对调查微量元素和甲状腺功能研究的文献综述.
- 分析微量元素在甲状腺激素合成和氧化应激中的生物化学作用.
- 特定微量元素水平与各种甲状腺疾病发生率的相关性.
主要成果:
- 微量元素 (Fe,Cu,Zn,Se,I) 对于甲状腺激素的产生和抗氧化剂的防御至关重要.
- 有毒元素 (Cd,Hg,Pb) 可以诱导氧化应激并破坏甲状腺功能.
- 微量元素如Fe,I,Mn,Zn和Se的不平衡与甲状腺功能低下,甲状腺结节,癌症和自身免疫性甲状腺炎有关.
结论:
- 微量元素在甲状腺健康中起着关键的双重作用,作为必需的营养素和潜在的毒素.
- 保持适当的微量元素度对于预防甲状腺功能障碍和疾病至关重要.
- 需要进一步研究微量元素在治疗甲状腺疾病中的治疗潜力.
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