饮食炎症评分 (DIS) 和生活方式炎症评分 (LIS) 对多发性硬化症严重程度的影响
Monica Guglielmetti1,2, Cinzia Ferraris1,2, Lenycia de Cassya Lopes Neri1,2
1Human Nutrition Center, Department of Public Health, Experimental and Forensics Medicine, University of Pavia, 27100 Pavia, Italy.
Nutrients
|February 13, 2025
概括
饮食和生活方式因素显示出与多发性硬化症 (MS) 严重程度的潜在联系. 虽然整体得分没有相关性,但特定的饮食成分,如绿叶蔬菜和生活方式因素,如体力活动和酒精消费,可能会影响MS的进展.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
背景情况:
- 多发性硬化症 (MS) 是一种以免疫为媒介的中枢神经系统疾病,其特征是炎症和化.
- 饮食和生活方式因素越来越多地被认为对MS发展和炎症过程的潜在影响.
研究的目的:
- 研究饮食和生活方式的炎症潜力与多发性硬化症的严重程度之间的关联.
主要方法:
- 一项涉及107名参与者的横截面研究评估了人口,神经和营养数据.
- 饮食炎症评分 (DIS) 和生活方式炎症评分 (LIS) 用既定的协议计算.
- 进行了统计分析,以评估DIS,LIS和MS严重程度得分 (MSSS) 之间的关系.
主要成果:
- 在整体DIS,LIS和MSSS之间没有发现显著的相关性.
- 特定的饮食成分,如绿叶蔬菜,与MS严重程度有关 (OR 1.67).
- 包括高体力活动 (OR 5.51) 和重度饮酒 (OR 5.61) 在内的生活方式因素与较低的MS严重程度有关.
结论:
- 虽然总的饮食和生活方式炎症评分与MS严重程度无关,但单个成分可能起作用.
- 需要进一步的干预研究来证实特定的饮食和生活方式因素对MS进展的影响.
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