人类的乳制品消费和结肠粘液相关的肠道微生物群-一项初步调查
Ellie Chen1, Nadim J Ajami2, Donna L White1,3,4,5
1Department of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Nutrients
|February 13, 2025
概括
乳制品的摄入影响肠道微生物群的多样性和组成. 较高的乳制品和牛奶消费与像Faecalibacterium和Akkermansia这样的有益细菌的增加相关,而奶酪摄入量显示了各种各样的关联.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 乳制品消费与可能受到肠道微生物群影响的健康结果有关.
- 了解饮食和肠道微生物组之间的关系对于健康至关重要.
研究的目的:
- 调查自我报告的乳制品摄入量与结肠粘膜相关的肠道微生物群之间的关联.
- 确定总乳制品,牛奶,奶酪和酸奶的消费如何影响微生物多样性和组成.
主要方法:
- 横截面研究分析了来自34个人的97个结肠粘膜活检.
- 16S rRNA基因测序以分析肠道微生物群.
- 使用多变量负二项式回归模型进行统计分析.
主要成果:
- 较高的总乳制品和牛奶摄入量与增加的α微生物多样性有关.
- 观察到Faecalibacterium和Akkermansia的相对丰度增加,总乳制品和牛奶消费分别较高.
- 较高的乳制品和奶酪总消费量与相对丰度的减少有关.
结论:
- 乳制品消费可能会调节结肠附着肠道微生物群的结构和组成.
- 研究结果表明,乳制品通过肠道微生物群对宿主健康的影响有潜在的机制.
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