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非洲猪瘟病毒载体疫苗开发进展

Yue Yang1, Hengxing Yuan1, Yulu Zhang1

  • 1State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Helmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, Shandong University, Qingdao 266237, China.

International journal of molecular sciences
|February 13, 2025
PubMed
概括

非洲猪瘟 (ASF) 对全球猪业构成重大威胁. 利用病毒,细菌或酵母平台对载体疫苗的研究对于开发针对非洲猪瘟病毒 (ASFV) 的有效疫苗至关重要.

关键词:
在ASFV抗原.非洲猪瘟是非洲猪瘟的一种疾病.细胞因子 细胞因子疫苗,疫苗的使用情况.矢量 矢量 是一个向量.

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Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...