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Updated: Jun 30, 2026

Generation of Genetically Modified Mice through the Microinjection of Oocytes
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Generation of Genetically Modified Mice through the Microinjection of Oocytes

Published on: June 15, 2017

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在羊中优化CRISPR/Cas9基因编辑系统 (Ovis aries) 卵细胞通过微注射

Haitao Wang1, Hengqian Yang1,2, Tingting Li1

  • 1State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

International journal of molecular sciences
|February 13, 2025
PubMed
概括

这项研究优化了羊卵细胞中的CRISPR/Cas9基因编辑,实现了畜牧养殖的高效率. 改进的方法成功生产了转基因羊,推进了分子设计育种策略.

关键词:
这就是CRISPR/Cas9的作用.基因编辑 基因编辑微注射微注射的方法羊群羊群羊群的羊群是什么意思

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CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...