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使用mRNA疫苗技术设计和表达Fasciola hepatica多形结构

Javier Sánchez-Montejo1, Tania Strilets2, Raúl Manzano-Román1

  • 1Infectious and Tropical Diseases Research Group (e-INTRO), Biomedical Research Institute of Salamanca Research Centre for Tropical Diseases at the University of Salamanca (IBSAL-CIETUS), 37007 Salamanca, Spain.

International journal of molecular sciences
|February 13, 2025
PubMed
概括

这项研究确定了针对寄生虫Fasciola hepatica的潜在疫苗. 这些,当结合到使用mRNA技术的多表位构造时,表现出高效的表达,为新疫苗铺平了道路.

关键词:
肝炎带 (Fasciola hepatica) 是一个肝炎带.免疫信息学是一种免疫信息学.它们是mRNARNA.酸是一种酸.疫苗,疫苗的使用情况.

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Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
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