跨支气管肺冷活检中不良事件对组织病理学诊断的影响
Kenji Tsumura1, Shushi Umemoto1, Yoshiaki Zaizen1,2
1Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
Journal of clinical medicine
|February 13, 2025
概括
跨支气管肺冷活检 (TBLC) 的不良事件,如出血,与较差的样本质量和诊断信心降低有关. 这影响了通过TBLC进行的间歇性肺病诊断的可靠性.
科学领域:
- 肺部病理学 肺部病理学
- 干预性肺病学 干预性肺病学
- 病理学 病理学 病理学
背景情况:
- 跨支气管肺冷活检 (TBLC) 与显著的不良事件发生率有关.
- 了解影响这些事件的因素对于患者安全和诊断准确性至关重要.
研究的目的:
- 调查TBLC相关不良事件与病理样本的质量/诊断之间的关系.
- 评估不良事件如何影响间歇性肺病 (ILD) 的诊断信心.
主要方法:
- 分析了一组102名接受TBLC以ILD诊断的患者.
- 研究了样本状况,病理诊断和不良事件 (出血,肺胸,急性恶化) 之间的关联.
主要成果:
- 副作用发生在18.6%的患者中,出血是最常见的 (13.7%).
- 经历不良事件的患者,特别是出血,样本取样成功率较低,诊断信心较低.
- 较低的病理信心水平与增加的TBLC相关不良事件有显著的相关性.
结论:
- 与TBLC相关的不良事件,特别是出血,可能会影响样本的充分性.
- 这些并发症与诊断信心降低有关,可能影响ILD诊断.
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