肥胖对青春期时间和男性生育能力的影响
Valeria Calcaterra1,2, Lara Tiranini3, Vittoria Carlotta Magenes2
1Department of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy.
Journal of clinical medicine
|February 13, 2025
概括
儿童肥胖会破坏男性青春期的时间,并对未来的生育能力产生负面影响. 早期发现和管理对于生殖健康至关重要.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 生殖健康 生殖健康
- 肥胖问题研究研究
背景情况:
- 儿童肥胖症显著影响青春期的发育和两个性别的激素变化.
- 肥胖对男性青春期的影响是复杂的,受代谢,荷尔蒙,遗传,表观遗传和环境因素的影响.
- 新出现的证据通过炎症标志物和改变精液质量,将儿童肥胖与男性生育能力受损联系在一起.
研究的目的:
- 审查儿童肥胖和男孩青春期发育之间的关系.
- 探索儿童肥胖对男性生育能力的影响.
- 综合当前关于肥胖,青春期和男性生殖健康相关机制的知识.
主要方法:
- 现有文献的叙述性审查.
- 对儿童肥胖,青春期时间和男性生育能力的研究进行分析.
- 综合了有关激素,炎症和表观遗传因素的发现.
主要成果:
- 肥胖对男孩青春期开始的影响是不一致的,一些研究显示加快,而另一些研究报告延迟青春期,特别是在严重的情况下.
- 肥胖通过改变内分泌功能,炎症和表观遗传变化,影响精液质量和活力,对男性生育能力产生负面影响.
- 低生育率和不育率是肥胖相关疾病的潜在结果.
结论:
- 儿童肥胖症对青春期的进展和未来的男性生育能力存在重大风险.
- 早期识别和干预策略对于减轻不良生殖健康结果至关重要.
- 需要进一步的研究来充分阐明这些关联,并制定有针对性的预防措施.
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