在接受冠状动脉血管检查的患者中,年龄相关的结果:在哪些子组中,年龄很重要? 来自大型回顾性注册表的结果
Lasse Kuhn1, Tobias Schupp1, Philipp Steinke1
1Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Journal of clinical medicine
|February 13, 2025
概括
接受冠状动脉血管造影的老年患者面临更高的心力衰竭再住院的风险. 晚年独立预测心力衰竭 (HF) 再入院,但不是急性心肌梗塞或再血管.
科学领域:
- 心脏病学 心脏病学
- 老年医学 老年医学
- 公共卫生 公共卫生
背景情况:
- 调查冠状动脉疾病 (CAD) 患病率,程度和长期结果的年龄相关差异.
- 解决了管理老龄化,多病症人口进行侵入性冠状动脉血管学 (CA) 的日益增长的挑战.
- 强调在未经选择的CA患者中,根据年龄分层对长期结果的有限研究.
研究的目的:
- 分析侵袭性冠状动脉血管学 (CA) 患者预后的年龄相关差异.
- 评估年龄组与心力衰竭 (HF) 再住院,急性心肌梗塞 (AMI) 和冠状动脉再血管化的长期风险之间的关联.
- 为了确定晚年作为一个独立的预测者对不良心血管结果后CA.
主要方法:
- 包括在2016年至2022年间连续接受入侵性CA的7520名患者.
- 患者分为年龄段的分层:40岁<60岁,60岁<80岁,80岁以上.
- 主要终点的评估:在36个月内因心力衰竭 (HF) 再住院,同时存在AMI和冠状动脉再血管化的风险.
主要成果:
- 随着年龄的增长,CAD的患病率和严重程度 (三血管CAD) 显著增加.
- 80岁以上的患者在36个月内出现了最高的HF再住院率 (28.4%),在多变量调整 (HR=1.265) 后,这种风险仍然显著.
- 在不同年龄组中,AMI和冠状动脉再血管化的发生率并没有显著差异.
结论:
- 高龄是长期心力衰竭再住院的独立预测因子,在接受CA的患者中.
- 冠状动脉疾病 (CAD) 的程度和严重程度随着年龄的增长而增加,但这与AMI或再血管化的风险增加无关.
- 优化心力衰竭 (HF) 的诊断和治疗策略至关重要,特别是在接受CA的老年患者身上.
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