相关实验视频

Updated: May 28, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

罗马尼亚西北部黑色素瘤:流行病学和组织病理学特征以及相关风险因素的分析

Adina Patricia Apostu^1,2, Loredana Ungureanu^1,3, Andra Piciu⁴

¹Department of Dermatology, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Journal of clinical medicine

|February 13, 2025

概括

这项研究描述了罗马尼亚的皮肤黑色素瘤 (CM),发现了关键的风险因素和亚型. 早期检测和预防战略对于减少该地区黑色素瘤负担至关重要.

科学领域:

皮肤病学皮肤病学
在瘤学瘤学.
流行病学流行病学

背景情况:

皮肤黑色素瘤 (CM) 是一个重大的健康挑战,特别是在中欧和东欧,有更高的晚期发病率和更低的存活率.
黑色素瘤的发病率和结果在地理位置上有所不同,需要局部流行病学表征.

研究的目的:

鉴定罗马尼亚西北部皮肤黑色素瘤 (CM) 的特征,并确定相关的风险因素.
为早期检测和初级预防黑色素瘤提供有针对性的公共卫生干预信息.

主要方法:

一项横截面队列研究,涉及172名在克卢日和比霍尔县的阴道病理学确诊黑色素瘤患者.
通过对人口统计,阳光照射,骨数和黑色素瘤特征的标准化问卷收集数据 (2023年1月 - 2024年5月).

主要成果:

诊断时的平均年龄为44岁,39%的病例显示布雷斯洛指数 (BI) >2毫米.
表面扩散的黑色素瘤 (SSM) 在女性中最常见,男性的结节性黑色素瘤 (NM) 最常见. 较高的BI与NM和状状黑色素瘤 (ALM) 相关联.
较年轻的诊断年龄与高神经数,室内活动和吸烟有关. 农村居民报告说,更多的太阳烧伤.

结论:

调查结果突出了针对黑色素瘤早期检测和预防的有针对性的公共卫生倡议的需要.
建立国家黑色素瘤登记处对于改善罗马尼亚的流行病学监测和减少疾病负担至关重要.

关键词:

流行病学流行病学黑色素瘤是一种黑色素瘤.有关风险因素的风险因素.

更多相关视频

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

相关概念视频

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Non-LTR Retrotransposons

Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...