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Updated: May 28, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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在nNOS/NO和COX-2之间的交叉增强了干扰素-马刺激黑色素瘤的进展

Anika Patel1, Shirley Tong1, Moom R Roosan2

  • 1Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, CA 92618, USA.

Cancers
|February 13, 2025
PubMed
概括

干扰素玛 (IFN-γ) 通过nNOS-NO和COX-2/PGE2通路之间的反循环促进黑色素瘤. 抑制这些途径,特别是HH044和celecoxib,抑制了瘤生长并提高了疗效.

关键词:
这就是Celecoxib.循环氧基因酶-2 (COX-2) 是一种酶.干扰素 - 玛 (IFN-γ) 干扰素黑色素瘤是一种黑色素瘤.nNOS 抑制剂的使用.神经元氧化合成酶 (nNOS) 的作用氧化 (NO) 是一种氧化.编程死亡链条1 (PD-L1) 编程死亡链条1 (PD-L1)质腺素E2 (PGE2) 是一种前列腺素.

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