高甲状腺症与成年人脂肪过多的肌肉参数之间的关联:初步研究
Francesca Greco1, Luciana Sicilia2, Giuseppe Seminara2
1Department of Movement, Human and Health Sciences, University "Foro Italico" of Rome, 00135 Rome, Italy.
Healthcare (Basel, Switzerland)
|February 13, 2025
概括
甲状腺激素如自由三甲状腺素 (FT3) 可能会影响超重和肥胖成年人的肌肉强度和性能. 这些影响似乎在男性和女性之间有所不同,即使甲状腺功能正常.
科学领域:
- 内分泌学 在内分泌学.
- 运动医学 运动医学
- 人体生理学 人体生理学
背景情况:
- 甲状腺激素 (THs) 与人体组成有关,但它们对超重/肥胖个体肌肉健康的影响尚不清楚.
- 这项研究探讨了THs和肌肉参数之间的关系,在过多脂肪质量的成年人中.
研究的目的:
- 研究甲状腺激素 (FT3,FT4,FT3/FT4比率) 对超重和肥胖成人的肌肉参数 (握力,肌肉性能) 的影响.
- 为了确定这些关联是否在两性之间存在差异.
主要方法:
- 对105名肥胖成人 (65名女性,40名男性) 的横截面研究 (BMI 33.5 ± 8.0 kg/m2).
- 通过生物电阻分析评估的身体组成.
- 通过手握测试 (HG) 和10次重复的椅子站测试 (CST) 测量的肌肉参数.
- 通过自由三甲状腺素 (FT3) 和自由甲状腺素 (FT4) 水平来评估甲状腺功能.
主要成果:
- 在女性中,FT3与握力 (HG) 有正相关,FT3/FT4比率与椅子站测试 (CST) 性能有负相关.
- 在男性中,FT3与骨肌肉质量正相关.
- 在两种性别中,THs和脂肪指数 (BMI,脂肪量) 之间没有发现显著的相关性.
结论:
- 甲状腺激素水平 (FT3,FT3/FT4) 在甲状腺功能良好的,超重/肥胖个体中可能会对男性和女性的肌肉参数产生不同的影响.
- 需要进一步的研究来阐明THs作为肌肉健康生物标志物的机制和潜力.
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