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Updated: May 28, 2025

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EphA2 和 SASH1 之间的萨姆-萨姆关联:在癌症相关突变的研究中

Marian Vincenzi1, Flavia Anna Mercurio1, Ida Autiero1

  • 1Institute of Biostructures and Bioimaging, National Research Council of Italy, Via Pietro Castellino 111, 80131 Naples, Italy.

Molecules (Basel, Switzerland)
|February 13, 2025
PubMed
概括

在SASH1无菌α基因1 (SASH1-Sam1) 中与癌症相关的突变可能会改变其与EphA2受体氨酸激酶的相互作用. 这项研究分析了这些突变如何影响SASH1-Sam1的稳定性和与EphA2的结合,这可能会影响癌症的进展.

关键词:
在 EphA2 中.中环 (ML) /终螺旋 (EH) 模型这就是SASH1的意义.萨姆-萨姆综合体是一个复杂的建筑群.癌症 癌症 癌症 癌症 癌症停靠的对接方式误解突变是一种错误的突变.分子动力学分子动力学结构预测 结构预测

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