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基因编辑用于增强猪产量:目前的进展和前景

Won Seok Ju¹, Seokho Kim¹, Jae-Yeong Lee¹

¹Animal Biotechnology Division, National Institute of Animal Science, Rural Development Administration, 1500 Kongjwipatjwi-ro, Iseo-myeon, Wanju-gun 55365, Republic of Korea.

Animals : an open access journal from MDPI

|February 13, 2025

概括

像CRISPR这样的基因编辑技术在猪中提供精确的基因修改,增强抗病能力和生产特征,使畜牧业更具弹性. 这些进步也为人类疾病研究创造了有价值的模型.

科学领域:

农业科学农业科学
生物技术是生物技术.
遗传学是一个遗传学.

背景情况:

传统的养猪业在遗传多样性,抗病能力和环境适应性方面面临着局限性.
基因编辑技术提供精确的基因修改来克服这些局限性.

研究的目的:

审查用于猪的基因编辑技术的进展.
探索优化猪遗传学的途径,以实现一个有弹性的畜牧业.
检查基因编辑对猪生产特征的影响及其在人类疾病建模中的作用.

主要方法:

综合了最近对基因编辑工具的研究,专注于CRISPR/Cas9及其在猪中的衍生物.
检查了这些工具用于增强抗病能力和生产特征的应用.
审查了基因编辑猪作为人类疾病模型的使用.

主要成果:

在向抗病基因方面取得了重大进展,包括对猪生殖和呼吸系统综合征病毒的免疫力.
基因编辑猪越来越多地被用作人类疾病的模型,展示了更广泛的应用.
进步解决了猪遗传多样性,抗病能力和环境适应性的局限性.

结论:

基因编辑通过增强关键特征和支持生物医学应用,为可持续畜牧业生产提供了巨大的潜力.
解决技术挑战 (非目标效应) 和道德问题对于实现猪基因编辑的全部潜力至关重要.
综合方法对于确保未来的性,道德和生产力畜牧业至关重要.

关键词:

这是一个CRISPR/Cas9系统.基因编辑基因编辑这是下一代测序.猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪

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