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Updated: May 28, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
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由于HPV E6对G6PD的调节失调,通过激活STAT3/PLOD2通路,使子宫癌恶化

Jie Zhang1,2, Wei Dong1,2, Qin Yang1,2

  • 1Department of Medical Genetics, Yunnan Provincial Key Laboratory for Birth Defects and Genetic Diseases, National Health Commission Key Laboratory of Preconception Health Birth in Western China, the First People's Hospital of Yunnan Province, Kunming 650100, P. R. China.

Carcinogenesis
|February 13, 2025
PubMed
概括

高风险的人类乳头瘤病毒 (HPV) 感染通过上调葡萄糖-6-酸脱酶 (G6PD),从而激活STAT3-PLOD2通路,驱动子宫癌 (CC). 这种机制促进了CC的进展,并提供了潜在的治疗点.

关键词:
宫癌:子宫癌是一种癌症.葡萄糖-6-酸盐脱酶.高风险的人类乳头瘤病毒16百科拉根-氨酸二氧格酸盐5-二氧基因酶2 2信号转换器和转录的激活器 3 3

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