相关实验视频

Updated: May 28, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

在初级婴儿绿眼中,使用Ologen植入物对抗mitomycin C的亚膜带切除术

Rehab R Kassem¹, Amanne F Esmael¹

¹Department of Ophthalmology, Cairo University, Cairo, Egypt.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

|February 13, 2025

概括

奥洛根植入物和米托米辛C (MMC) 在治疗初级先天性玻璃眼的疗效和安全性相似. 使用Ologen植入物的重新手术应推迟至手术后至少4个月.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
手术干预手术干预

背景情况:

初级先天性玻璃眼 (PCG) 是一种严重的玻璃眼形式,需要有效的手术治疗.
用菌素C (MMC) 增强的亚膜管切除术 (SST) 是一种常见的治疗方法,但正在探索替代辅助方法.

研究的目的:

为了比较辅助米托菌素C (MMC) 增强的脑下带切除术 (SST) 与Ologen植入物的疗效和安全性,作为初级先天性玻璃眼的二次手术.

主要方法:

一项对38只用MMC (17只眼睛) 或Ologen植入物 (21只眼睛) 进行SST的眼睛的回顾性研究.
眼内压力 (IOP) ≤18 mmHg对于婴儿<1岁和≤20 mmHg对于年长的孩子定义成功的结果.
主要终点在5-9个月,次要终点在最后一次随访.

主要成果:

这两组在初级 (47.1% MMC vs 47.6% Ologen) 和二级终点 (47.1% MMC vs 52.4% Ologen) 上表现出相似的成功率.
在MMC组中,IOP的降低在整个过程中都是显著的,而Ologen组从术后4个月开始显示出显著意义.
两组之间没有观察到白内障或瞳孔异常等并发症的显著差异.

结论:

原体植入物是MMC的可行的替代品,用于增强初级先天性玻璃眼中的SST,显示出类似的疗效和安全性.
在用Ologen植入物治疗的病例中,临床医生应避免在早期 (4个月前) 重复手术,以确保足够的愈合和效果.

关键词:

可生物降解的原基质植入物.这是一种Ologen.这就是为什么Bleb Bleb Bleb.眼内压力眼内压力米托Mycin C 的使用情况.一次性先天性玻璃眼.原发性婴儿眼光 (英语:primary infantile glaucoma) 是一种儿童眼光.下面的状带切除术.

更多相关视频

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction

Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction

Published on: October 13, 2017

相关概念视频

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...