被忽视的成人PFAPA综合征
Aiping Zhang1, Ruifeng Zhang1, Yiling Jiang1
1Department of Hematology, Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 201999, China.
Radiology case reports
|February 13, 2025
概括
周期性发烧,口腔口炎,耳炎和宫腺炎 (PFAPA) 综合征在成年人中很罕见,并且经常被误诊. 通过延长发烧间隔,早期诊断和菌素治疗可以显著改善生活质量.
科学领域:
- 内部医学 内部医学
- 类风湿病学 类风湿病学
- 儿科 儿科 儿科
背景情况:
- 周期性发烧,口腔口炎,耳炎和宫腺炎 (PFAPA) 综合征是一种罕见的自身炎症性疾病.
- 成年人的诊断是具有挑战性的,往往导致延迟或不正确的治疗.
- 成人发病的PFAPA综合征可以模仿其他疾病,如喉炎或淋巴腺炎.
研究的目的:
- 为了突出诊断成人发病PFAPA综合征的挑战.
- 强调在患有反复发烧和宫淋巴腺炎的成年人中考虑PFAPA的重要性.
- 提出一个案例,证明胆固醇在治疗成人PFAPA的有效性.
主要方法:
- 一个69岁的女性患有PFAPA综合征的病例报告.
- 对诊断挑战和治疗结果的审查.
- 分析菌素对发烧复发和生活质量的影响.
主要成果:
- 患者最初被误诊,并接受了无效的抗生素治疗.
- 胆固醇治疗显著延长了发烧发作之间的间隔.
- 实现的最长无发烧间隔为8个月,改善了患者的生活质量.
结论:
- 成人发病的PFAPA综合征需要高度的临床怀疑,特别是当出现复发性发烧和宫淋巴腺炎时.
- 抗生素治疗对于PFAPA综合征是无效的.
- 胆固醇是一种有效的治疗PFAPA综合征,改善患者的治疗结果和生活质量.
相关概念视频
Prosopagnosia
123
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
123
Antisocial Personality Disorder
44
Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
Behavioral Characteristics and...
Behavioral Characteristics and...
44
Oppositional Defiant Disorder
23
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
23
Alzheimer's Disease: Overview
432
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
432
Pneumonia II: Pathophysiology
210
The pathophysiology of pneumonia involves the following steps:
210
Pneumonia V: Nursing management and Prevention
1.8K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
1.8K


