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Updated: May 28, 2025

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阿波利波蛋白E在神经退行性疾病中的多功能作用

Sadequl Islam1, Arshad Noorani2, Yang Sun1

  • 1Department of Neuro-Oncology, Graduate School of Medical Sciences, Institute of Brain Science, Nagoya City University, Nagoya, Japan.

Frontiers in aging neuroscience
|February 13, 2025
PubMed
概括

阿波利波蛋白E (ApoE) 基因变异显著影响阿尔茨海默病 (AD) 风险. ApoEε4等位基因增加了风险,而ApoEε2提供了保护,影响了AD和其他神经退行性疾病中的Aβ,tau和神经炎症.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.帕金森病是帕金森氏症的一种疾病.粉样蛋白-β (Aβ) 是一种骨髓缩侧面硬化症 (ALS) 是一种亚脂蛋白 E 是一种非脂蛋白 E.神经退行性疾病的神经退行性疾病

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