长期COVID-19中的心血管结果:系统审查和元分析
Ting Zhang1, Zhimao Li1, Qimin Mei1
1State Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
长期COVID-19显著增加了心血管疾病的风险,包括心力衰竭和高血压,感染后的几周. 后COVID-19护理必须优先监测幸存者的心脏健康.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 越来越多的证据将SARS-CoV-2感染与急性期后的心血管并发症联系在一起.
- 这些COVID-19后的心血管表现需要全面的表征.
研究的目的:
- 系统地审查和元分析COVID-19后个人心血管疾病的流行率.
- 为了量化SARS-CoV-2感染后心血管并发症的风险.
主要方法:
- 8项队列研究 (近1000万个人) 的系统审查和元分析.
- 在主要数据库 (PubMed,EMBASE等) 进行搜索. 从2019年12月开始到2022年6月.
- 随机效应元分析用于比较COVID-19幸存者与对照者的心血管疾病患病率.
主要成果:
- 长期COVID-19与血栓塞栓性疾病,冠状动脉疾病,中风,心律失常,心肌病,心肌炎,高血压,心力衰竭和心脏性休克的风险增加有关.
- 在长期COVID病例中观察到心肌病,深静脉血栓和高血压的综合风险差异显著更高.
- 特定危险比率表明SARS-CoV-2感染后各种心血管疾病的风险增加.
结论:
- 从急性COVID-19中恢复后四周或更长时间内,心血管疾病的风险显著增加.
- 对于幸存者而言,急性后COVID-19护理必须强调心血管健康监测.
- 心血管健康的积极管理对于COVID-19后的长期恢复至关重要.
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