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评估紫外线辐射对人类皮肤组织的影响,使用双曝光数字全息干扰计

Gloria Frausto-Rea¹, María Del Socorro Hernández-Montes¹, Fernando Mendoza Santoyo¹

¹Centro de Investigaciones en Óptica, León, México.

Journal of biomedical optics

|February 13, 2025

概括

紫外线 (UV) 辐射通过改变皮肤的位移和硬性而改变人体皮肤. 数字全息干扰测量 (DHI) 量化了这些紫外线引起的变化,为皮肤健康和护理提供了洞察力.

科学领域:

生物医学光学生物医学光学
皮肤病学皮肤病学
生物物理学的生物物理.

背景情况:

人体皮肤容易受到来自自然和人工来源的紫外线 (UV) 辐射的损伤.
暴露于紫外线辐射会导致皮肤结构和机械性能发生变化.
评估这些变化对于了解皮肤健康和制定保护措施至关重要.

研究的目的:

评估不同剂量的紫外线辐射对人类皮肤组织样本 (HST) 的影响.
利用数字全息干扰测量 (DHI) 作为一种非侵入性工具,用于量化紫外线引起的皮肤变化.
确定移位和刚度作为UV辐射对皮肤影响的生物标志物.

主要方法:

人体皮肤组织样本 (HST) 经过双曝光数字全息干扰测量 (DHI).
声波诱导了表面振动,DHI监测了位移.
皮肤硬度是从位移幅度计算出来的,与紫外线暴露水平相关.

主要成果:

暴露于紫外线辐射导致皮肤位移和硬度发生显著变化.
在紫外线能量剂量和位移之间发现了负相关性,与硬度有正相关性.
DHI成功地区分了受辐射和未受辐射的皮肤组织,在预测皮肤衰老和脱水方面有潜在的应用.

结论:

数字全息干扰测量 (DHI) 是一种有效的非侵入性光学技术,用于评估紫外线辐射对皮肤的影响.
DHI提供伪3D相位图来量化表面移位和刚度.
这种方法为皮肤护理和保护皮肤疾病提供了潜在的好处.

关键词:

数字全息干扰计数字全息干扰计.人类皮肤组织皮肤组织机械反应机械反应紫外线辐射是一种紫外线辐射.

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