美国人口中饮食炎症指数和骨质疏松症之间的关联:来自NHANES 2003-2010年的证据
Zhiwen Liu1, Huanling Jian2, Zijing Peng1
1The Third Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Frontiers in nutrition
|February 13, 2025
概括
更高的饮食炎症指数 (DII) 与骨质疏松症风险增加有关. 减少饮食性炎症可能有助于预防骨质疏松症,强调饮食对骨健康的重要性.
科学领域:
- 营养科学 营养科学
- 骨健康研究 骨健康研究
- 流行病学 流行病学
背景情况:
- 骨质疏松症是一个重要的公共卫生问题.
- 饮食模式影响慢性疾病的风险.
- 饮食诱导的炎症在骨质疏松症中的作用需要进一步研究.
研究的目的:
- 调查饮食炎症指数 (DII) 与美国人口骨质疏松症患病率之间的关联.
- 为了确定有助于骨质疏松风险的特定饮食因素.
- 开发基于饮食因素的骨质疏松风险预测模型.
主要方法:
- 分析了2003-2010年国家健康和营养检查调查 (NHANES) 的7290名参与者的数据.
- 权重多变量逻辑回归和受限立方线回归 (RCS) 来评估DII与骨质疏松症的关系.
- 最小绝对收缩和选择操作员 (LASSO) 回归以确定关键的饮食因素和风险预测的诺莫格拉姆构造.
主要成果:
- 与对照组相比,骨质疏松症患者的DII得分显著更高 (1.61对1.18,p < 0.001).
- 最高的DII四分位数与88%的骨质疏松症风险增加有关 (OR:1.88,95%CI:1.41-2.52,P趋势<0.001).
- 纳米图包括已识别的饮食因素,显示出强大的预测准确度,AUC为83.6%.
结论:
- 较高的DII分数与较高的骨质疏松症患病率密切相关.
- 减少饮食性炎症是预防骨质疏松症的潜在策略.
- 饮食模式在骨质疏松风险评估和管理中起着至关重要的作用.
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