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Updated: May 28, 2025

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

肥胖儿科急性淋巴细胞白血病患者的阿斯巴拉金酶暴露和毒性概况的变化

John C Panetta¹, Emily Ashcraft², Sima Jeha³

¹Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis.

|February 13, 2025

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Combination Therapies and Personalized Medicine

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...