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Updated: May 3, 2026

Murine Aortic Crush Injury: An Efficient In Vivo Model of Smooth Muscle Cell Proliferation and Endothelial Function
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新型直接重编程的平滑肌细胞促进血管再生作为微血管壁细胞

Cholomi Jung1,2, Ji Woong Han3, Shin-Jeong Lee2

  • 1Department of Internal Medicine (C.J., E.J.L.), Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.

Circulation
|February 13, 2025
PubMed
概括

使用特定因子直接将人体纤维细胞编程为收缩平滑肌细胞 (SMCs),创造了一种新的细胞疗法. 这些重编程的SMC (rSMC) 有效地修复了血管损伤,并促进了缺血四肢的血管形成.

关键词:
细胞重编程技术纤维细胞缺血症肌细胞,光滑肌肉新血管化,生理细胞细胞复原过程

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