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而SESN1则对STING1进行负面调节,以维持先天性免疫均质

Lingxiao Xu1,2, Hongqian Zhang3, Zuocheng Qiu4

  • 1Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Autophagy
|February 13, 2025
PubMed
概括

塞斯特林1 (SESN1) 负面调节STING1信号传递,对免疫恒温至关重要. 缺少SESN1增强了抗病毒防御,而其补充则减少了狼等自身免疫性疾病的炎症,表明了治疗潜力.

关键词:
自自是一种自的过程.降解降解是一种降解.这就是SESN1的原因.一个刺1 一个刺1免疫系统的恒常性.

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