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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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对C-2替代型皮拉佐洛皮里米丁和胺基异体的综合计算分析 ALLINI: 3D-QSAR,分子对接和ADMET研究

Aakanksha Kunwar1, Gondaliya Krishna N1, Vijay M Khedkar2

  • 1School of Applied Material Sciences, Central University of Gujarat, Gandhinagar 382030, Gujarat, India.

Current HIV research
|February 13, 2025
PubMed
概括

这项研究探讨了新型C2-pyrazolopyrimidine胺基作为人类免疫缺陷病毒 (HIV) 潜在的全osteric整合酶抑制剂. 研究确定了增强对HIV-1整合酶 (IN) 的抑制活性的关键结构特征,为药物开发提供了新的途径.

关键词:
3D-QSAR 是一个3D-QSAR.承认,这是一个错误.艾利尼斯 (ALLINIS) 公司在C2-pyrazolopyrimidines中使用.在LEDGF/p75中使用.电静电潜力的电静电潜力分子对接的分子对接.链转移抑制剂 链转移抑制剂范德瓦尔斯是什么意思

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