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Updated: May 28, 2025

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
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显微镜丸精子提取在46,XY性别发育的差异由5-α减少酶2型缺乏引起的5-α减少酶类型2

Joao Paulo Greco Cardoso1, Berenice Bilharinho Mendonça2, William Carlos Nahas1

  • 1Divisão de Urologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

Archives of endocrinology and metabolism
|February 13, 2025
PubMed
概括

显微丸精子提取 (micro-TESE) 可能为患有5-α减少酶2型缺乏症 (5ARD2) 的男性提供生育选择,这是一种性别发育差异的形式. 早期的手术纠正对于保护这些独特患者的生育潜力至关重要.

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The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
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