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在怀孕期间使用的混合闭环治疗系统的案例系列

Trinity L Brigham^1,2, Matthew P Klein², Janet K Snell-Bergeon²

¹School of Public and Population Health, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA.

Acta diabetologica

|February 13, 2025

概括

在1型糖尿病 (T1D) 怀孕中使用Tandem Control IQ的混合闭环 (HCL) 疗法改善了血糖控制. 这种非标签的使用显示了从第一次诊所访问的积极结果,满足大多数目标.

科学领域:

内分泌学在内分泌学.
生殖医学生殖医学
医疗技术医疗技术医学技术

背景情况:

怀孕期间的1型糖尿病 (T1D) 带来了重大的血糖管理挑战.
混合闭环胰岛素疗法 (HCL) 提供了一个潜在的解决方案,但其在妊娠期间的有效性尚未研究.
很少有研究研究了在T1D孕妇中使用商业上可用的HCL系统的情况.

研究的目的:

评估非标签混合闭环 (HCL) 治疗在1型糖尿病 (T1D) 影响的怀孕中的有效性.
为了评估T1D怀孕的血糖控制参数和妊娠健康结果,使用特定的HCL系统进行管理.
确定在妊娠期间使用Tandem Control IQ系统的可行性和影响.

主要方法:

追溯对15例1型糖尿病 (T1D) 怀孕的回顾,这些怀孕是使用Tandem Control IQ HCL系统来管理的.
收集的数据包括基线特征,持续血糖监测 (CGM) 度量,胰岛素的使用和胰岛素剂量.
分析了孕期特异性和标准血糖指标,以及妊娠健康结果.

主要成果:

在大多数怀孕期间,HCL系统有助于实现怀孕特定的时间范围 (psTIR) 目标.
孕期特定的时间下方范围 (psTBR) 和时间上方范围 (psTAR) 度量通常保持在预期的范围内.
怀孕初次检查后,血糖指标显示有所改善,特别是在非标签HCL使用的辅助技术下.

结论:

在T1D怀孕中非标签使用Tandem Control IQ HCL疗法与改善的血糖控制有关.
血糖水平从第一个诊所访问开始就有所提高.
妊娠健康结果与预期的T1D复杂的怀孕结果一致.

关键词:

妊娠健康结果的结果血糖目标是指血糖水平的目标.混合动力闭环环路的混合动力.怀孕怀孕怀孕怀孕双重控制智商 (IQ) 是一个智商.第1类糖尿病患者.

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