过敏的外视网膜功能障碍 过敏的外视网膜功能障碍
Yizhe Cheng1, Xinyu Liu1, Jinglin Lu1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
JAMA ophthalmology
|February 13, 2025
概括
在发烧后突然视力丧失的儿科患者表现出扩散的外视网膜干扰. 大多数人在一年内恢复了显著的视力敏度,尽管电网膜学仍然异常,这表明一种不同的情况.
科学领域:
- 眼科医生 眼科 眼科
- 儿科视网膜 儿科视网膜
- 神经眼科神经眼科
背景情况:
- 儿童突然,严重的双边视力丧失是罕见的,需要及时诊断.
- 识别儿科视网膜疾病的模式有助于工作和预后.
研究的目的:
- 描述临床表现,视网膜成像发现和儿科患者突然严重双侧视力丧失的1年预后.
- 为了调查发烧性疾病和儿童外视网膜干扰之间的联系.
主要方法:
- 一个多中心病例系列,包括8名儿科患者 (16只眼睛) 在发烧后出现突然视力丧失.
- 进行了临床评估,视网膜成像 (包括圆形区域和外部限制膜评估) 和电视网膜学 (ERG).
- 后续评估包括视觉敏度,视野和视网膜成像超过1年.
主要成果:
- 所有患者都经历了发烧后的双边视力突然丧失,眼,扩散圆形区域 (EZ) 和外部限制膜 (ELM) 干扰.
- 视力敏度显著改善,88%的人在一年后达到20/40或更好.
- 在所有患者中,ERG显示形和棒反应灭,尽管视力恢复,但仍然存在.
结论:
- 发烧后儿童的一个明显的,潜在的未被认可的疾病是突然视力丧失和外视网膜破坏的特征.
- 对于这个实体,建议使用术语"超急性外视网膜功能障碍".
- 需要进一步的研究来阐明病理生理学和这种情况的最佳管理.
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