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变化PM_2.5度及其主要成分在怀孕期间对血压的影响

Peiyao Chen¹, Wenjie He¹, Yan Jin¹

¹Department of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China.

Journal of hazardous materials

|February 13, 2025

概括

在怀孕期间暴露于微颗粒物 (PM_2.5) 组分,如酸盐,显著影响母亲的血压 (BP),特别是缩BP. 减少城市污染源对于孕产妇健康至关重要.

科学领域:

环境健康环境健康
心血管流行病学心血管流行病学
生殖健康生殖健康

背景情况:

颗粒物 (PM_2.5) 的组成部分,包括硫酸盐,酸盐,,有机物和黑碳,构成了PM_2.5质量的很大一部分.
这些成分以其心血管毒性而闻名,但它们对妊娠期心血管健康的具体影响仍未得到充分研究.

研究的目的:

调查PM_2.5成分变化与妊娠血压 (BP) 变化之间的关联.
确定哪些特定的PM_2.5成分在怀孕期间对母亲心血管健康构成最大风险.

主要方法:

一项前性队列研究,涉及中国广州的1913名孕妇 (2017-2020年).
在怀孕早期和晚期进行了重复的办公室血压测量.
用追踪空气污染数据集估计了PM_2.5成分度.

主要成果:

PM_2.5质量及其组成部分的变化与妊娠期血压变化有显著的相关性 (β = 1.88-3.42,P < 0.001).
在PM_2.5成分和BP之间观察到一个反转的U形非线性关系,没有明确的值.
系统性血压 (SBP) 对PM_2.5成分变化的敏感性更高,颗粒酸盐是主要的贡献者.

结论:

PM_2.5质量和成分的变化,特别是颗粒酸盐,与怀孕期间母亲的血压变化有关.
调查结果强调需要采取更严格的排放控制措施,以减少城市空气污染并保护孕产妇的心血管健康.

关键词:

血压血压血压血压变化变化变化组件组件组件组件在PM{2.5) 中,怀孕怀孕怀孕怀孕

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