在接受阿达利穆马布治疗的患者中出现了创伤性脑下皮层血瘤
Anthony V Nguyen1, Bronson M Ciavarra1, Muralidhar Jatla2,3
1Department of Neurosurgery, Baylor Scott and White Health, Temple, Texas.
Pediatrics
|February 13, 2025
概括
一个罕见的创伤性脑下血液瘤 (SDH) 病例发生在接受阿达利姆巴治疗的儿科患者身上. 患者在手术后康复并转换为乌斯提金巴,这表明阿达利木巴和SDH之间存在潜在联系.
科学领域:
- 儿科神经学 儿科神经学
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
背景情况:
- 在儿科患者中,创伤性皮血瘤 (SDH) 是不常见的.
- 生物疗法Adalimumab被FDA列为SDH的潜在原因,但临床报告很少.
研究的目的:
- 在接受阿达利穆马布治疗的患者中报告小儿性创伤性亚体皮质血瘤病例.
- 讨论在这个患者群体中阿达利穆马布和SDH之间的潜在关联.
主要方法:
- 一名16岁的男性患有性结肠炎,接受阿达利木马布治疗,出现神经症状.
- 部成像显示出一个显著的左侧腹腔内血瘤与中线转移.
- 进行了血液瘤的手术疏散,并排除了其他病因.
主要成果:
- 患者被诊断出患有慢性腹腔内血瘤.
- 手术后的康复取得了成功,患者被转移到ustekinumab.
- 在停止服用阿达利穆马布后,没有观察到SDH的复发.
结论:
- 这一案例突出显示了在接受阿达利穆马布治疗的儿科患者中罕见的创伤性脑下皮质血瘤.
- 停止服用阿达利木马布和开始服用乌斯特基木马布导致了有利的结果.
- 需要进一步调查阿达利穆马布和SDH之间的潜在联系.
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