儿童急性通用脱血性 pustulosis 在一个孩子
Vineeta Pande1, Mrinali Thakur2, Nakul Pathak1
1Paediatrics, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth University, Pune, Maharashtra, India.
BMJ case reports
|February 13, 2025
概括
急性全身外血性 pustulosis (AGEP),在儿童中罕见的药物反应,可以在使用 cefixime 后表现出来. 用皮质类固醇和抗组胺剂迅速治疗导致儿童病例的快速康复.
科学领域:
- 皮肤病学 皮肤病学
- 儿科 儿科 儿科
- 药理学 药理学是指药理学的学科.
背景情况:
- 急性全身脱血性 pustulosis (AGEP) 是一种罕见的,严重的皮肤不良反应.
- 虽然经常与抗生素有关,但儿童的AGEP很少被报告.
- 一种常见的抗生素Cefixime可能会触发AGEP.
研究的目的:
- 在口服塞菲西姆后,报告小儿病患者罕见的AGEP病例.
- 要突出临床表现,诊断发现和儿童AGEP的管理.
- 强调承认AGEP作为儿科患者群体潜在的不良药物反应的重要性.
主要方法:
- 一个儿科病人出现发烧,咳和感冒的病例报告.
- 临床观察皮疹的发展,其特征是红血的基础与无菌的尖性疹.
- 实验室调查,包括血液图,肝脏和功能测试.
- 治疗方案包括停止使用cefixime,口服皮质类固醇和抗组胺药物.
主要成果:
- 患者在开始服用cefixime的24小时内出现了广泛的皮疹和疹.
- 实验室测试显示轻度白细胞瘤与正常的肝脏和功能.
- 在开始治疗后48小时内观察到临床改善,皮疹消失和脱皮.
结论:
- AGEP是一种罕见但显著的药物不良反应,可能发生在儿童身上.
- 早期识别和及时管理,包括药物戒断和皮质类固醇治疗,对于有利的结果至关重要.
- 这一案例凸显了儿童患者暴露于塞菲西姆或类似药物的需要提高对AGEP的认识.
相关概念视频
01:31Pulmonary Tuberculosis III
296
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
296
01:23Skin Diseases and Disorders
2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
01:23Hand hygiene
3.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.1K