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Updated: May 28, 2025

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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氧化物和翻译后修改对调节α-晶素的陪伴功能的影响

Khuraijam Surjalal Singh1, Snigdha Krishna1, Akshita Gupta1

  • 1Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India.

Progress in molecular biology and translational science
|February 13, 2025
PubMed
概括

阿尔法晶体素是一种内在无序的蛋白质,通过防止蛋白质聚合来保持透镜的透明度. 糖化会损害其陪伴功能,增加糖尿病患者白内障的风险.

关键词:
伴侣类活动 (CLA)本质上是无序的蛋白质.氧化物溶解物 (osmolytes) 是一种溶解物.后翻译修改后的修改.α-Crystallinallin 的使用情况.

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