相关实验视频

Updated: May 28, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

患有多动症儿童执行功能和注意力的神经相关:对基于任务的功能连接研究的ALE元分析

Meng Wang¹, Jing Yu², Hyun-Duck Kim³

¹College of Sports Science, Shenyang Normal University, Shenyang, China; Department of Physical Education, Keimyung University, Daegu, Republic of Korea.

Psychiatry research

|February 13, 2025

概括

这项元分析揭示了注意力缺陷多动症 (ADHD) 儿童的独特大脑激活模式,显示了关键执行功能领域的活动减少和其他领域的活动增加,为ADHD病理提供了新的见解.

科学领域:

神经科学是一个神经科学.
发展心理学发展心理学
医疗成像医学成像

背景情况:

注意缺陷多动性障碍 (ADHD) 是一种流行的神经发育障碍.
执行功能和注意力缺陷是ADHD的核心症状.
基于任务的功能性MRI (fMRI) 是研究ADHD脑功能的一个关键工具.

研究的目的:

对基于任务的fMRI研究进行全面的元分析,研究ADHD儿童的执行功能和注意力.
为了确定ADHD儿童和神经类型对照之间的大脑激活差异的一致模式.
阐明ADHD相关认知缺陷的神经生物学基础.

主要方法:

对2023年3月20日之前发表的研究,在主要数据库 (PubMed,Cochrane Library,Web of Science,EBSCO,Embase,Scopus) 进行了系统的文献搜索.
使用激活概率估计 (ALE) 的元分析来综合包含的研究中的fMRI数据.
分析了57项涉及2231名参与者 (1062名ADHD患者) 的研究.

主要成果:

在患有ADHD的儿童中,在前侧双关节网络,门,胰岛,环状回环和中回环中观察到显著的低活化.
在ADHD中的过度活化在叶,下垂,中额前和副海马中被注意到.
具体发现包括头顶叶参与,额叶和脑干异常,以及刺激剂未使用儿童的活性变化.

结论:

ADHD的特点是大脑激活在多个网络中的广泛变化,包括对执行功能和注意力至关重要的网络.
前面双面网络和条纹体之间的功能障碍连接可能会损害工作记忆.
重点强调小脑在抑制控制和注意力任务中的作用,这表明它在ADHD病理学中的重要性.

关键词:

在ALE的元分析中.注意力注意力注意力注意力注意力缺陷多动障碍注意力缺陷多动障碍孩子孩子孩子孩子执行职能执行职能执行职能

更多相关视频

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

相关概念视频

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Information Processing Approach

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...