喉外表现的喉回流病的喉外表现
1Department of Surgery, University of Auckland, PO Box 99743, Newmarket, Auckland 1149, New Zealand.
Otolaryngologic clinics of North America
|February 13, 2025
概括
喉回流 (LPR) 可以导致鼻炎和睡眠呼吸暂停等喉外问题. 有效的管理侧重于改变生活方式和抗炎治疗,而不仅仅是抑制酸性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 肺部病理学 肺部病理学
背景情况:
- 喉回流 (LPR) 的喉外表现已被认可,但机械途径需要进一步的证据.
- 累积的证据将LPR与包括中耳炎,鼻炎,阻塞性睡眠呼吸暂停,牙侵蚀和呼吸道狭窄等疾病联系在一起.
- 酸在LPR症状产生中的作用有限,这表明质子抑制剂 (PPI) 可能不是一种普遍有效的治疗方法.
研究的目的:
- 审查LPR在各种喉外疾病中的作用的证据.
- 评估LPR目前治疗模式的有效性.
- 为LPR提出一个更有效,多方面的管理策略.
主要方法:
- 对调查LPR及其相关条件的研究进行文献综述.
- 对酸和其他因素在LPR症状学中的作用的分析.
- 对PPI治疗结果的评估与综合管理方法对比.
主要成果:
- 慢性肺炎越来越多地与诸如鼻炎,阻塞性睡眠呼吸暂停和炎症性肺病等疾病有关.
- 酸性反流起到较小的作用;PPI治疗往往无法提供持续的缓解.
- 多方面的管理,包括行为改变和抗炎策略,显示出更大的有效性.
结论:
- 在喉之外,LPR有不同的喉外表现.
- 对许多LPR患者来说,质子抑制剂是不够的;需要采取更广泛的方法.
- 综合行为,保护和抗炎措施的综合管理对LPR更有效.
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