诊断与癌症治疗相关的心血管毒性:多模式整合方法和未来发展
Simon Travers1, Joachim Alexandre2, Lauren A Baldassarre3
1INSERM UMR-S 1180, Université Paris-Saclay, 91400 Orsay, France; Laboratoire de Biochimie, DMU BioPhyGen, Hôpital Européen Georges Pompidou, AP-HP, 75015 Paris, France.
Archives of cardiovascular diseases
|February 13, 2025
概括
诊断癌症治疗引起的心脏问题是复杂的. 新的生物标志物和先进的成像技术正在改善癌症患者心血管毒性的检测和管理.
科学领域:
- 心脏瘤学 - 心脏瘤学
- 发现生物标志物的发现.
- 心血管医学 心血管医学
背景情况:
- 来自癌症疗法的心血管毒性带来了诊断挑战.
- 复杂的癌症治疗和癌症与心脏病之间的相互作用使心脏瘤学复杂化.
- 目前的诊断方式包括血清生物标志物,成像和节律监测.
研究的目的:
- 审查目前心脏瘤学中的生物标志物和诊断策略.
- 突出在评估癌症疗法的归因性方面的挑战.
- 探索生物标志物研究和诊断准确性的新兴进展.
主要方法:
- 对当前心脏瘤诊断工具的综述:热波宁,尿素,心声图,心脏MRI,CT血管图和心电图.
- 讨论评估癌症治疗相关心血管毒性的局限性.
- 探索新的方法,包括基于病理生理学的血清生物标志物,先进的成像和远程监测.
主要成果:
- 目前的基石包括热素,尿性,多式成像和心电图.
- 评估癌症治疗对心血管健康的直接影响仍然很困难.
- 血清生物标志物,成像技术和远程监测正在取得进展.
结论:
- 需要改进的生物标志物来提高心脏瘤学诊断的准确性.
- 未来的方向涉及多参数运算和深度学习,用于先进的生物标志物开发.
- 这些创新承诺在诊断和管理与癌症治疗相关的心血管毒性的新时代.
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