选择太多,价值太少:通过选择具有成本效益的质子抑制剂来节省潜在的成本
1Department of Public Health, Mokwon University, Daejeon, South Korea. haeyoungkwon0111@gmail.com.
在韩国,将德克斯兰索普拉作为首选的质子抑制剂 (PPI) 转换为德克斯兰索普拉,每年可以节省超过4000亿韩元. 这种转变促进了成本效益高的处方,并提高了医疗保健的可持续性.
科学领域:
- 药物经济学 药物经济学
- 医疗保健服务研究 医疗服务研究
- 药物使用研究 药物使用研究
背景情况:
- 韩国缺乏全面的措施来促进具有成本效益的处方.
- 在398种产品中研究了15种质子抑制剂 (PPI) 的处方者决策.
研究的目的:
- 分析门诊PPI处方模式和处方者实践中的10年趋势.
- 通过合理的药物使用和具有成本效益的首选药物选择,估计潜在的医疗保健节省.
主要方法:
- 来自国家健康信息数据库的韩国门诊PPI处方数据 (2013-2022) 的回顾性分析.
- 计算PPI支出和使用的年度趋势 (定义的每日剂量).
- 确定了具有成本效益的PPI,并使用迪里克莱特分布模拟了潜在的节省.
主要成果:
- 门诊PPI成本在10年内每年上13.0%.
- 大多数处方的PPI (easomprazole,rabeprazole,tegoprazan) 的价格都很昂贵.
- 德克斯兰索普拉是最具成本效益的PPI (KRW 522.7/DDD).
- 推德克斯兰索普拉可以节省404.24亿韩元 (47.0%的当前支出).
结论:
- 在韩国的PPI处方中存在显著的节省成本的机会.
- 向具有成本效益的个人保护药物指导决策可以提高处方效率.
- 促进成本有效的处方提高了国家医疗保健系统的可持续性.
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