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Updated: May 28, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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波蒂明A毒素通过ZAKα依赖的NLRP1炎症酶激活引起皮肤炎症

Léana Gorse1, Loïc Plessis2,3, Stephen Wearne4

  • 1Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, Toulouse, France.

EMBO molecular medicine
|February 13, 2025
PubMed
概括

来自Vulcanodinium rugosum的海洋毒素导致了塞内加尔渔民的严重皮肤疾病. 毒素PortimineA破坏细胞功能,并通过ZAKα-NLRP1通路引发炎症,突出显示新的环境健康威胁.

关键词:
环境毒素环境毒素NLRP1 炎症性酶体利博毒性应激反应的应激反应皮肤病理 皮肤病理

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