与不洁净燃料相关的眼睛健康风险:元分析和系统审查
Shi-Hang Chen1, Yuan Tang1, Song Xue1,2
1National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China.
Frontiers in public health
|February 14, 2025
概括
不洁净的燃料 (UCF) 显著影响眼睛健康,增加白内障和视力障碍的风险. 眼睛症状如刺激和红色是UCF暴露的可靠指标.
科学领域:
- 眼科医生 眼科 眼科
- 环境健康 环境健康
- 公共卫生 公共卫生
背景情况:
- 不洁净的燃料 (UCF) 是一个主要的全球健康问题,特别影响呼吸系统健康.
- UCF与眼部健康之间的联系,包括白内障和视力障碍等疾病,需要全面调查.
研究的目的:
- 系统地审查和元分析不干净的燃料 (UCF) 与各种眼部健康结果之间的联系.
- 调查UCF对白内障,视力障碍和眼部不适等疾病的具体影响.
主要方法:
- 从三个数据库中对28项研究进行了元分析和系统审查,遵循MOOSE和PRISMA指南.
- 使用纽卡斯尔-太华尺度进行质量评估,使用I平方统计学进行异质性分析,使用埃格尔和贝格测试进行出版偏差评估.
主要成果:
- 在UCF暴露和白内障 (OR 2.29),视力障碍 (OR 1.70) 和一般眼睛疾病/症状 (OR 2.03) 之间发现了显著的关联.
- UCF特别影响了核白内障 (OR 1.98) 但不是皮质白内障. 严重的视力障碍,包括夜盲和失明,与UCF暴露有关.
- 眼部症状如水 (OR 3.20),眼部刺激 (OR 2.58) 和红眼 (OR 2.03) 显示与UCF暴露有很强的相关性.
结论:
- 不洁净的燃料 (UCF) 显著影响眼睛健康,特别是引起眼睛症状,白内障和视力障碍.
- 与UCF暴露相关的白内障患病率存在人口差异,自我报告的眼睛症状可以表明UCF暴露.
相关概念视频
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:17Accessory Structures of the Eye
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
01:22Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
01:22Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...