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在黑色素瘤中,NFATC2向基因特征与免疫检查点阻塞抗性相关

Bashir Lawal1,2, Yue Wang1,2, Parisa Lotfinejad1,2

  • 1UPMC Hillman Cancer Center, University of Pittsburgh Pittsburgh, PA 15213, USA.

American journal of cancer research
|February 14, 2025
PubMed
概括

激活T细胞2核因子 (NFATC2) 基因特征预测黑色素瘤中对免疫检查点抑制剂 (ICI) 的耐药性. 高的NFATC2得分表明反应和生存率不佳,这表明它是ICI治疗的生物标志物.

关键词:
NFATC2的目标基因组 (TGS)这种T-流离失所的瘤.抗PD-1免疫疗法免疫疗法免疫透 免疫透是什么?免疫疗法耐药性 免疫疗法耐药性黑色素瘤是一种黑色素瘤.

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