相关实验视频
Updated: May 28, 2025
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
23.2K
SARS-Cov-2 感染作为花细胞瘤中的 катехоламин危机:一个病例报告
Roberto Novizio1, Andrea Corsello2, Gaetano Emanuele Rizzo3
1Unit of Endocrinology and Diabetology, Catholic University of The Sacred Heart, Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Endocrine, metabolic & immune disorders drug targets
|February 14, 2025
概括
感染SARS-CoV-2可能会在患有染细胞瘤的患者中引发危及生命的上腺危机. 在COVID-19爆发期间,建议对这些患者进行密切的血压监测和增加α-阻断剂剂量.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 主要导致病毒性肺炎,但可以表现为内分泌并发症.
- 乳腺红细胞瘤,罕见的上腺髓瘤,由于不受管制的甲基荷胺释放引起症状,这种症状可以由各种压力因素引发.
- 之前还没有记录过SARS-CoV-2感染在染细胞瘤患者中导致上腺激素危机的可能性.
研究的目的:
- 报告患有由SARS-CoV-2感染引起的染细胞瘤的患者发生上腺危机的情况.
- 突出监测和管理在这个特定的患者群体的重要性.
主要方法:
- 一名63岁的男性患有已知的右上腺染细胞瘤,正在等待手术,出现高血压危机和昏.
- 患者在入院时检测出SARS-CoV-2阳性.
- 管理包括调整阿尔法阻断剂 (多克萨佐辛) 剂量和对高血压危机和COVID-19的支持性护理.
主要成果:
- 患者在SARS-CoV-2感染后经历了高血压危机和多余catecholamine的症状.
- 随着多克萨佐辛剂量增加,症状改善和血压控制得到了改善.
- 患者从SARS-CoV-2感染中恢复过来,并经历了成功的染细胞瘤手术,没有并发症.
结论:
- 上腺危机是一种严重的,危及生命的疾病,可由SARS-CoV-2感染在染细胞瘤患者中引起.
- 密切的血压监测和严格遵守药物治疗对于在等待手术的叶红细胞瘤患者至关重要,特别是在COVID-19爆发期间.
- 增加α阻断剂剂量可能是这种人群中对上腺素危机的必要预防措施.
更多相关视频
13:35A Convenient Method for Extraction and Analysis with High-Pressure Liquid Chromatography of Catecholamine Neurotransmitters and Their Metabolites
Published on: March 1, 2018
14.6K
06:39Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
15.6K
相关概念视频
01:30Adrenergic Agonists: Therapeutic Uses
719
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
719
01:27Adrenergic Neurons: Neurotransmission
3.3K
Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or adrenergic neurons. Noradrenaline, dopamine, adrenaline, or epinephrine are collectively called "catecholamines" as they contain a catechol moiety and an amine side chain. The five stages of neurotransmitter release involve their synthesis, storage, release, reuptake and metabolism.
Synthesis: Catecholamine synthesis requires tyrosine, which...
Synthesis: Catecholamine synthesis requires tyrosine, which...
3.3K
01:27Adrenal Gland Disorders
1.3K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.3K
01:18Adrenergic Agonists: Therapeutic Classification
698
Adrenergic agonists can be classified based on their therapeutic uses and mechanisms of action. They serve various purposes in clinical applications.
Vasopressor or pressor agents: They increase blood pressure and function as cardiac stimulants. Examples include endogenous catecholamines (norepinephrine and dopamine) and synthetic agents (phenylephrine).
Bronchodilators: β2-agonists can relax bronchial muscles and widen airways. They are commonly used for treating obstructive pulmonary...
Vasopressor or pressor agents: They increase blood pressure and function as cardiac stimulants. Examples include endogenous catecholamines (norepinephrine and dopamine) and synthetic agents (phenylephrine).
Bronchodilators: β2-agonists can relax bronchial muscles and widen airways. They are commonly used for treating obstructive pulmonary...
698
01:30Adrenergic Agonists: Direct-Acting Agents
1.3K
Drugs that mimic the action of endogenous catecholamines like noradrenaline and adrenaline are called adrenergic agonists or sympathomimetics. Based on their mechanism of action, sympathomimetics can be classified as direct-, indirect-, or mixed-acting sympathomimetics. Direct-acting adrenergic agonists activate adrenoceptors without affecting presynaptic neurons, making them independent of neuronal catecholamine-depleting agents like reserpine and guanethidine.
These agents can be classified...
These agents can be classified...
1.3K
01:18Disorders of the Autonomic Nervous System
519
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
Raynaud's disease, also known as Raynaud's...
519