一个基于家庭的战略,以识别和预防早发性心血管疾病:一个可行性试点研究
Pierre Charleux1, Niki Procopi1, Ghilas Rahoual1
1Sorbonne Université, ACTION Study Group, INSERM UMRS 1166, Institut de Cardiologie, Hôpital Pitié-Salpêtrière (AP-HP), Paris, 75013, France.
European journal of preventive cardiology
|February 14, 2025
概括
一项基于家庭的心血管风险评估发现了心血管疾病 (CVD) 的重大家族负担. 许多年轻的亲属可以从主动的初级预防中受益,但吸引无症状成年人仍然是一个挑战.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 遗传学 遗传学 是一个
背景情况:
- 目前的心血管疾病 (CVD) 预防指南不充分地针对年轻人,即使有已知的家族病史.
- 需要改进的策略来识别和预防风险较小的年轻人群中的心血管疾病.
研究的目的:
- 评估基于家庭的常规心血管风险评估的可行性和可接受性.
- 评估被诊断患有早发性冠状动脉疾病 (CAD) 的个人的一级亲属.
主要方法:
- 患有早发性CAD的患者确定了现有的心血管疾病,并先前在一级亲属中进行检查.
- 鼓励亲属寻求咨询进行心血管评估,如果他们健康,没有先前的心脏病随访.
- 初步评估的资格是由已知的心血管疾病或活跃的初级预防缺乏所定义的.
主要成果:
- 在137名患有早发性CAD的试验者中,评估了626名一级亲属.
- 24.4%的亲属患有心血管疾病; 19.6%患有冠状动脉疾病 (CAD).
- 在兄弟姐妹和成年儿童中,13.7%被诊断为心血管疾病,19.3%接受初级预防,64.2%有资格接受初步评估. 只有11.1%的人在12个月内开始查.
结论:
- 观察到心血管疾病的显著家族负担.
- 三分之二的年轻亲属提出了积极主动初级预防的机会.
- 让无症状的成年人参与基于家族病史的心血管查带来了挑战.
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