使用天然草药物质的困难及其在某些药物剂型中的当前使用
Ece Özcan Bülbül1, Neslihan Üstündağ Okur2
1Department of Pharmaceutical Technology, Faculty of Pharmacy, Istinye University, Istanbul, Turkey.
Current pharmaceutical design
|February 14, 2025
概括
天然草药产品显示出治疗癌症和糖尿病等疾病的潜力,但配方和知识方面的挑战阻碍了它们的使用. 进一步的研究对于克服这些障碍和将草药纳入治疗方案至关重要.
科学领域:
- 药理学和民族植物学
- 自然产品化学 自然产品化学
- 综合医学是一个整体医学.
背景情况:
- 草药产品在全球范围内广泛用于健康,但它们的有效性可能会因随机使用而受到损害.
- 缺乏对自然物质的标准化配方和使用指南会带来风险.
- 对于癌症和糖尿病等慢性疾病的现有治疗选择缺乏新的草药干预措施.
研究的目的:
- 审查制定和利用天然草药物质的挑战.
- 突出植物化合物在各种疾病中的治疗潜力.
- 弥合草药的传统使用和科学验证之间的差距.
主要方法:
- 使用主要科学数据库进行了全面的文献搜索:科学直接,PubMed和谷歌学者.
- 对天然草药物质及其应用的现有研究进行系统审查.
- 对研究的分析,重点是疾病治疗的局限性和有效性.
主要成果:
- 全球使用天然草药物质存在重大挑战,包括知识差距和有限的技术资源.
- 尽管存在困难,但目前的研究表明,某些天然草本物质对抗癌症,微生物感染,糖尿病,认知和心血管疾病的有效性.
- 有证据表明,在管理复杂的健康状况时,特定的植物性化合物具有治疗作用.
结论:
- 进一步深入研究对于解决与天然草药相关的局限性至关重要.
- 提高可靠性和标准化协议是将草药物质纳入主流医疗实践的关键.
- 需要增加科学研究,以支持这些天然化合物的临床应用在疾病治疗中.
相关概念视频
01:28Factors Influencing Drug Absorption: Pharmaceutical Parameters
113
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
113
01:27Factors Influencing Drug Absorption: Drug Dissolution
400
The pharmacokinetic journey of drugs from solid oral dosage forms into systemic circulation is multifaceted. It begins with disintegration, a prerequisite ensuring a solid dosage form's subdivision into minute particles. Dissolution occurs next as these granulated entities solubilize in gastrointestinal fluids. This solubilization is crucial for the succeeding stage, permeation, which describes the traversal of the drug across the intestinal membrane and its subsequent entry into the blood...
400
01:27Effects of Chemicals: Overview
1.2K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
1.2K
01:02Prescription, Nonprescription and Orphan Drugs
681
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
681
01:21Factors Affecting Drug Response: Overview
1.8K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
1.8K
01:28Biopharmaceutics and Pharmacokinetics: Overview
1.8K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
1.8K