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质母细胞瘤免疫疗法的发展趋势:二十年的图书统计分析

Zhi Long^1,2,3, Zhenjie Yi^1,2,3, Wei Yan⁴

¹Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.

Human vaccines & immunotherapeutics

|February 14, 2025

概括

本文献计量研究分析了从2004年至2024年间的质母细胞瘤免疫治疗研究. 主要趋势包括免疫检查点抑制剂和CAR T细胞疗法,美国在这一关键癌症治疗领域的全球领先贡献.

科学领域:

神经瘤学神经瘤学
免疫学免疫学免疫学
图书统计学图书统计学

背景情况:

由于瘤异质性和免疫抑制,质母细胞瘤的预后不佳.
免疫疗法为质母细胞瘤提供了一个有前途的治疗策略.
对质母细胞瘤免疫治疗趋势的系统图书法分析很少.

研究的目的:

进行对质母细胞瘤免疫治疗研究的文献分析.
确定2004年至2024年的研究热点,趋势和关键贡献者.

主要方法:

从科学网络核心集合 (2004-2024) 中对3729篇论文进行了图书统计分析.
使用VOSviewer和CiteSpace来分析出版物数据,关键字和引用模式.
审查的国家,研究所,期刊,作者和关键词贡献.

主要成果:

美国在出版 (1708篇) 和引用 (90,590篇) 方面领先,其次是中国 (926篇) 和德国 (349篇).
主要期刊包括临床癌症研究和神经瘤学.
主要关键词:temozolomide,放射治疗,树突细胞,细胞毒性T淋巴细胞,疫苗接种.
新兴热点:免疫检查点抑制剂和仿真抗原受体T细胞疗法.

结论:

质母细胞瘤免疫疗法研究正在迅速推进,在全球有着显著的贡献.
免疫检查点抑制剂和CAR T细胞疗法代表着重点和未来发展的关键领域.
这一分析提供了关于质母细胞瘤免疫疗法研究不断发展的景观的见解.

关键词:

图书统计学分析在CiteSpace中使用CiteSpace.在VOSviewer中使用VOSviewer.质母细胞瘤 (glioblastoma) 是一种免疫疗法免疫疗法

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